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Davis–Beirut reaction
The Davis–Beirut reaction is used to synthesize diversified 2H-indazoles and indazolones.
The Davis–Beirut reaction converts a 2-nitrobenzylamine to a 2H-indazole by treatment with aqueous base in an alcoholic solvent. The product is thought to have potential application as a medicine, perhaps by development of myeloperoxidase inhibitors, which could offer treatment for inflammatory diseases such as cystic fibrosis and rheumatoid arthritis.〔(AUB professor etches Beirut's name in chemistry history ). ''American University of Beirut News''. 9 Oct 2013〕
The reaction was discovered by Mark Kurth and Makhluf Haddadin and discussed in publications about 2005. In their seventh paper on the subject, Kurth and Haddadin named it after the universities where they work, University of California, Davis and American University of Beirut.〔(【引用サイトリンク】 ‘Davis-Beirut Reaction’: Town recognizes gown, and vice versa )〕
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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